LEUKEMIA

Formerly known as Hepatitis non A non B. It is self-limiting disease transmitted by water or food contamination by faeces of patients. Incubation period : 2-9 weeks Agent : hepatitis E virus is the causative agent. Host : Mainly young adults, 15-40 years Infection during pregnancy is responsible for abortions, intrauterine death & high...
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Two forms of the disease viz, (1) Schilling type and (2) Naegeli type have been recognized. Schilling type – arising directly from the reticulo-endothelial system. Naegeli type – arising from myeloid tissue, more rapid course, usually terminates as myeloid leukaemia. Affects all age group, no sex preference. Onset insidious, often death in a few...
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ACUTE LYMPHATIC LEUKEMIA Highest incidence in the first five-year of life; relatively rare after the age of 25; onset – sudden with fever, rigor, prostration, aching pains in the limbs, and haemorrhage beneath the skin or in the mouth. Bone and joint pains, enlargement of lymph glands, little enlargement of spleen. May present as...
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ACUTE MYELOID LEUKEMIA Commonly in children and young adults; more males. The onset is often sudden ; high rise of temperature, pain in the back and limbs, a sore throat, and bleeding from the gums. Rapidly progressing anaemia, tenderness over the sternum and other bones. In the terminal stage , enlarged spleen and liver,...
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The Leukemia are characterized by an abnormal hyperplasia of the leucopoietic tissues. A peripheral blood examination most often reveals a high leucocyte count, many of the cells being immature. In a number of cases, the peripheral blood may not show any characteristic feature of Leukemia, yet a bone marrow examination reveals plenty of immature...
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